Ingredient name record

RETINOL

Korean search label: 레티놀

Evidence at a glance

1official function labelsIngredient context 1selected human studiesNot a full review 1selected legal receiptsNot a compliance verdict 40product recordsRecorded occurrences

Evidence coverage, not an efficacy or safety score.

Identity & coverage details

Official CosIng inventory context recorded; chemical identity and the complete current regulatory profile remain unverified; selected human studies available; selected EU legal text available.

Recorded presence is not a safety rating, recommended dose or benefit claim.

Identity and formulation context

Names are indexed using case and whitespace normalization. Botanical, chemical and marketing identities have not been independently equated.

The study tested a specific retinol lotion with controlled staff application. It does not prescribe use of any product in this library.

Discovery spellings and aliases

all-trans retinol · pure retinol · retinol · vit a · vitamin a · 레티놀 · 비타민 a · 비타민a · 순수 레티놀 · 순수레티놀

Search-only metadata; an alias is not proof of chemical equivalence.

Functions listed by CosIng

SKIN CONDITIONING - MISCELLANEOUS

Inventory functions describe the ingredient entry, not a finished product’s effects.

How this inventory match is used

The European Commission’s CosIng inventory is informational. An entry is not permission to use an ingredient or a safety assessment. Listed functions describe the inventory entry; they do not establish a finished product’s effects. The match uses the exact ingredient name, with case and whitespace normalization.

RETINOL · Inventory identifiers

Inventory record: 37479 · Active
CAS identifiers in this entry: 68-26-8 / 11103-57-4
EC identifiers in this entry: 200-683-7 / 234-328-2
Inventory restriction references: III/376
References require checking the current legal text; they are not a complete restriction assessment.

Checked 2026-10-02 · Read the official CosIng entry

Human study context

Primary publications checked 2026-10-02. These are selected studies, not a systematic review, safety rating or instructions for using a product.

Improvement of Naturally Aged Skin With Vitamin A (Retinol)

2007 · Original journal article reviewed

Material tested: Retinol in a 0.4% lotion
Study design: Randomized, double-blind, vehicle-controlled comparison between arms.
Participants: 36 elderly participants, average age 87; 23 completed all visits.
Concentration and schedule in the study: 0.4% retinol lotion applied by study staff to one arm up to three times weekly for 24 weeks.
What the authors reported: The investigators reported a greater reduction in fine-wrinkle scores with retinol than with vehicle.

What this does not establish

Arm skin in elderly participants does not establish the same effect on facial skin or younger populations.
Thirteen participants withdrew; three withdrawals involved skin irritation or itching.
Small biopsy subgroups limit interpretation of biochemical results.
Retinol findings are not transferred to retinal, retinoic acid or retinyl esters.

Read the original publication

Still unverified

This is a partial literature record, not a systematic review.
These study preparations have not been matched to any Treatfolio product, batch or concentration.
Chemical identity, the complete current regulatory profile and finished-product effects remain unverified.

Selected regulatory text

These dated legal texts are ingredient context, not a complete current legal assessment or proof that a product complies.

European Union · Annex III, entry 376

Commission Regulation (EU) 2024/996 · Published 2024-04-04 · Text checked 2026-10-02

Covered products: Vitamin A ingredients specified by this entry; body lotion versus other leave-on/rinse-off products.
Limits in this text: Body lotion: 0.05% retinol equivalent (RE). Other leave-on and rinse-off products: 0.3% RE.
Conditions: The entry requires a vitamin A warning about considering daily intake.
Transition dates: Noncompliant products cannot first be placed on the EU market from 1 November 2025; they cannot continue to be made available from 1 May 2027.

Selected amendment only; later changes and finished-product compliance are not assessed.

Read the official legal text